Caring for your heart, cares for your brain also. The Risk Factors(RF) for CHD are RF’s for Alzheimers Disease(AD) Cerebrovascular Disease(CVD)and all Atherovascular Disease, as well as OWOB and DM. We can include Hypertension, Metabolic Syndrome and the Epithelial cancers and potentially more organ cancers too.As CHD is the planets leading killer, the disease that is most likely to kill us, effecting what’s good for our heart, will be good for all degenerative diseases!
When I graduated from Medical School the ‘Common Soil’, ‘Common Origin’, hypothesis was darting about in the neurones and axons of some in medicine but was far from acceptance, because evidence was scanty. Medicine and surgery has evolved via organ systems and diseases. Now we recognise disease pathologies manifesting in many organ systems, we refer to as the systemic effects. It seems the evidence argues for a common origin, in a common period, perhaps commencing at the Neolithic time.
The collection of diseases in the first paragraph may arguably account for most of the mortality and morbidity of our species now globally. Most, perhaps all the RF’s are common to all, they have a common origin. In my publication, Stone Agers in the Wrong Lane, I propose that biologically the template was fashioned about homosapiens during the Neolithic period, when the species appears to have chosen a change in life practice and nutrition, such that biochemically and metabolically, we experienced a significant ‘loss’, change of micronutrients, chemical elements, protein, all fats, fibre and CHO. This was a major biological event for species homosapiens. This was not a diet fad from one of the glossy magazines. This was not based on scientific evidence, it was a species evolutionary adaption, or decision failure and still is. I believe it played a major role in the population explosion of the planet later, providing nutritionless calories, fetal, infant and maternal survival, with poor immunity for survival with time and poor disease avoidance for longevity.We tended to survive better at pregnancy, birth and into an early adulthood that expanded the population, but poor nutrition stunted life expectancy. Good shelter, clean water, air, sanitation, better reproduction were needed to very slowly extend life expectancy in the affluent world.
As you will be aware from other posts, the Neolithic period is discussed as though it was a well defined period with common well defined changes and practices and of course it was anything but. Arising sporadically, in patches, variously over the last 10-12,000 years, with no uniformity and spread, where homosapiens resided slowly. The historical documentation of Colonialism has revealed most of the world up to 200 years ago, Africa, Americas, most of Asia, Australasia, Pacific, had not adopted Neolithic changes and often subsequently only to a minor or mixed extent!! Yes, for 99.5% of our time on the planet we have been hunter-gatherers. All of the hunter-gatherer groups studied until recently, were not afflicted with the degenerative diseases, the list in the first paragraph. You do not need to have graduated in Medicine to recognise, the Neolithic life practices and particularly nutrition, played a part in the origin of our degenerative diseases.Skeletal evidence of shortened long bones, cranial cavity, pelvis with bone atomic studies, reveal the changes of protein, micronutrient, malnutrition.
But we are living longer, it must have been good for us Dr. Green. Everyone knows that, its in the papers, magazines, official documents, radio, TV etc., We are told to save and provide for our ‘long’ retirement. Its a comfortable rationalisation, a ‘health slogan’, to serve our denial of reality, fear of too close an analysis!I spent a chapter in Stone Agers explaining who is living longer and why. If you were born in the ‘Period of Decadence’, after WWII, per capita life expectancy is falling in the affluent world and markedly in the non-affluent world, which consists arguably of 60-70% of the world population.The current ‘bulge’ in the ‘aged’ is due to the ‘Baby Boom’, post WWII. They are riddled with degenerative diseases and are responsible for the expensive, excessive demand of current ‘Health’ services in the affluent world.Yes we are living longer than in 1900 in the affluent world, for the reasons I outlined. We have ‘trumped’ that with a life practice and gustatory anarchy during the period of ‘decadence’ since WWII. No, by contracting OWOB, Hypertension, DM, CHD, MS, cancer, AD at record levels, does not make you live longer!!!Its not a new deceptive medical ‘vaccination’, to help you live longer, expensively, painfully, miserably.Why is ‘Euthenasia’ gaining popularity?
Poor analysis and understanding of disease and disease behaviour, by too many who should not be doing it, has and is deceiving the public of the current and impending reality.Medicine has been credited with increasing the life expectancy of the affluent world, which is true to a point, but not for the reasons the public perceive , if they are asked. In general terms the improvement and availability of food, shelter, adequate clothing, clean water, sanitation, clean air for respiration have been our earliest important contributors to improved morbidity and mortality in the affluent world, arguably the largest contributor. Education and work are critical in affluent societies now.Medicine has demonstrated their necessity for survival and reproduction.The deficiency in food nutritionally has and does vary over time and place as do the other factors and its impact has been more subtle.
If politics and pressure groups are removed from the analysis of life expectancy in the affluent world, immunisation, improved neonatal, infant and maternal mortality are the most potent contributing factors to improvement in life expectancy in the latter 20th century.
Medical clinicians have known for a long time that the treatment and management of discrete pathologies such as CHD, AVD, hypertension, OWOB, DM had commonality;the patient with effort angina needed less medication when they sensibly exercised, lost weight, stopped smoking, reduced alcohol, even reversed hypertension and diabetes. Now we have added AD and certain cancers to the list.For too long these diseases were portrayed as episodes of bad luck. Increasingly the community slowly accepts these diseases are self inflicted diseases and clinicians need co-operation from patients to avoid and treat them.
The two proteins TAU intracellular and beta Amyloid extracellular found in the brains of patients with AD, before the symptoms of AD and perhaps in some who don’t develope symptoms, seem removed from other pathologies in the degenerative diseases list ie, CHD, AVD, DM, OWOB, hypertension etc.,But, their risk factors are near identical and AD as an example, does not arise without these risk factors.At this stage it seems that organ response to common risk factors determines the different diseases. A patient who has CHD, AVD, DM, OWOB, hypertension, which is common in the community, is at significant risk for AD and too many cancers.
What and when do the early factors, changes arise? The epigenetic influences on a fetus in gestation of a OWOB mother, will be the first in this context.Fortunately that will not be the case universally, but in a society where 65-75% of adult women are OWOB, the odds are stacked against the fetus.Biologically the fetus interprets the future extra-uterine world from its mother, who is OWOB, with hyperinsulinemia, hyperglycemia, chronic inflammation and reproduces a similar template. The latter can be avoided if the infant evolves with appropriate nutrition, which initially is breast milk and later food with lowCHO and sugar. Smoking, alcohol, vegetable oils and processed food are later risk factors.
Yes, it had its origins with Neolithic practice and nutrition, but human aggregation, urbanisation, work, economy, industrial changes and population explosion, with migration and colonisation all contributed to the evolution and growth of these diseases.
A reminder; Colonial medicine did not recognise this collection of diseases amongst the hunter-gatherers of the New World, until with time, they adopted Colonial European nutrition and life practices,ie alcohol and tobacco.The nutrition change was broadly incorporating wheat flower and sugar into prepared or processed foods, that lead to overloading of CHO, hyperinsulinemia, they were not metabolically adapted for. Yes, insulin levels increased, from CHO demand; resistance arose and this sequence must arguably be the genisis of our degenerative disease cohort.
Some believe there is a silver lining in all adversity.I am sure you have spotted it. There is a staggering morbidity and mortality caused by this cohort of diseases, so by having a ‘common origin’, basis, cause, means their treatment, avoidance has a common origin too!! So if we attend to CHD avoidance, treatment, it will impact the other diseases too!Why CHD? Because it is our leading acute and chronic killer.
A final ‘common soil’ comment. Since the early 1950’s increasing evidence of decreasing sperm counts in a collection of counties has recently been confirmed, accompanied by poor quality sperm. At this stage OWOB and smoking are accepted RF’s. I would speculate that pre-diabetes and diabetes would be RF culprits too as they are in women. Diabetic neuropathy, autonomic neuropathy, small vessel vasculopathy of diabetes are responsible for erection and ejaculation dysfunction, so testicular malfunction is feasible. This has alarmed some in medicine as it could interfere with future reproduction.But if metabolic changes and or chemical RF’s are responsible, the issue is reversible, if hs co-operates!! Or should this be seen as another hs Darwinian maladaption that potenially could aid survival with a much smaller planet population?Remember the Mumps virus: a tinkering with its genetics by an innocent scientist could make global aspermia a reality. Yes we need sperm banks.